ANTIDIABETIC AND ANTIOXIDANT ACTIVITIES OF SIX EDIBLE MUSHROOMS GROWN IN BANGLADESH

Abstract

Executive Summary Six species of edible mushrooms are commercially available in Bangladesh, namely, Pleurotus ostreatus (PO2), Pleurotus djmore (POP), Pleurotus sajor-caju (PSC), Pleurotus citrinopileatus (PY), Pleurotus florida (FLO), Pleurotus cystidiosus (PCYS). Methanol and water extracts were prepared from these edible mushrooms and their antioxidant activity and α-glucosidase inhibitory activity were studied. The water extract of Pleurotus djmore (POP) had the highest total phenolic content (30.8 mg GAE/g sample extract) and the highest DPPH scavenging activity (IC 50 : 0.33 mg/mL). Likewise, the methanolic extract of Pleurotus djmore (POP) showed the highest α-glucosidase (from Saccharomyces cerevisiae) inhibitory activity (IC 50 :

1.27 mg/mL). The outcomes suggested that Pleurotus djmore (POP) can be utilized for the development of α-glucosidase (S. cerevisiae) inhibitory activity and antioxidant activity.